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$3.7 million funding boost for infection prevention and control in aged care
Four exceptional research teams will share in over a $3.7 million funding boost under the National Health and Medical Research Council’s (NHMRC) Targeted Call for Research (TCR): Improving infection prevention and control in residential aged care homes 2023.

Novel vaccines to prevent hearing loss lead to learning and life outcomes
Almost all Aboriginal and Torres Strait Islander children living in remote areas have ear problems that start from within weeks of birth. For many, otitis media (‘glue ear’) leads to hearing loss and devastating learning and life outcomes.

Tracker - 29 July 2024
Welcome to Tracker, NHMRC’s fortnightly newsletter with the latest information on major activities and funding opportunities.

Speaking of Science: International Research Translation Practice
Knowledge gained through research underpins improvements in Australia's health and medical services. This research can be fundamental or can be applied, directly addressing clinical problems, public policy, quality of life and environmental health issues or the provision of health services.

Clear line of sight to solving irreversible vision loss
As a practising optometrist, Associate Professor Zhichao Wu realised there was a big problem diagnosing glaucoma. Glaucoma is a leading cause of irreversible vision loss that is projected to cost Australia $4.3 billion per annum by 2025.

$7 million to target Aboriginal and Torres Strait Islander health
Five expert research teams will share in an investment of $7 million in funding to support targeted health and medical research into the commercial determinants of Aboriginal and Torres Strait Islander health.

Research Excellence: Structure, function, and modulation of peptide hormone G protein-coupled receptors
Professor Patrick Sexton is the Professor of Pharmacology at the Monash Institute of Pharmaceutical Sciences and is the Director at the ARC Centre for Cryo-electron Microscopy of Membrane Proteins. Professor Sexton is a leader in progressing our understanding of G protein-coupled receptors (GPCRs), particularly allosteric modulation and biased agonism, and applying cryo-EM to study structure and dynamics of GPCRs. He is a Clarivate Analytics highly cited researcher and an elected Fellow of the British Pharmacological Society (BPS). Professor Sexton is also the co-founder of Septerna Inc and DACRA Tx and has been the recipient of many awards for his scientific contributions that have had major impacts on biological chemistry research.

Tracker - 15 July 2024
Welcome to Tracker, NHMRC’s fortnightly newsletter with the latest information on major activities and funding opportunities.

Celebrating a 25-year legacy of Aboriginal and Torres Strait Islander health research with NHMRC
Professor Yvonne Cadet-James, the pioneering researcher, academic, mentor, registered nurse and midwife is celebrating a 25-year legacy of Aboriginal and Torres Strait Islander health research at the National Health and Medical Research Council (NHMRC).

Research Excellence: Advancing health equity of the Aboriginal and Torres Strait Islander population
Associate Professor Odette Pearson is of Eastern Yalanji and Torres Strait Islander descent and coleads the Aboriginal Health Equity Theme, South Australian Health and Medical Research Institute. Her research focus is improving chronic disease and ageing outcomes of Aboriginal and Torres Strait Islander peoples through policy and guideline development and implementing and evaluating real world health and social interventions. Aboriginal leadership, governance and community and cross sector partnerships are foundations of her research. A/Prof Pearson has received the Lowitja Institute Patricia Anderson Leader in Aboriginal Research (2023), UniSA Alumini Award for Research in Aboriginal Health (2022) and The Diane Ranck, SAHMRI award for Leadership in Research (2022).

New Joint Committee Announcement
Welcome to this special edition of Tracker.

Driving a new era in Australian health and medical research
The National Health and Medical Research Council (NHMRC) and the Medical Research Future Fund (MRFF) will work more closely under a new structure announced today.

Tracker - 1 July 2024
Welcome to Tracker, NHMRC’s fortnightly newsletter with the latest information on major activities and funding opportunities

Speaking of Science: International Men’s Health Week
For the 30th anniversary of International Men’s Health Week (10–16 June 2024), NHMRC shined an important light on key issues impacting the health and wellbeing of Australian men and boys, focusing on the 3 pillars of health: physical, mental and emotional.

Research Excellence: Developing novel gene expression control mechanisms for ALS gene therapies
Professor Roger Chung is the Professor of Neurobiology and Neurochemistry, and Deputy Dean (Research and Innovation) in the Faculty of Medicine, Health and Human Sciences at Macquarie University. Professor Chung’s research employs a multi-disciplinary approach to understanding the biochemical, molecular and cellular mechanisms that underpin how neurons respond to injury or neurodegenerative disease, and how non-neuronal cells (glia) are involved in modulating this process. Professor Chung is the co-founder and Chief Scientific Officer of CelosiaTX and also leads the Neurochemistry and Molecular Therapeutics Group within the Macquarie University Centre for Motor Neuron Disease Research.

NHMRC update on the Australian Drinking Water Guidelines
The National Health and Medical Research Council (NHMRC) plays a pivotal role in safeguarding public health by developing the Australian Drinking Water Guidelines (the Guidelines). These guidelines serve as a crucial resource for water regulators and suppliers, offering comprehensive advice on monitoring and managing drinking water quality across Australia.

Research Excellence: Driving the transition to high value testing to benefit the health of all
Professor Katy Bell is a clinical epidemiologist and health services researcher at the Sydney School of Public Health. Professor Bell’s research evaluates the clinical effectiveness of healthcare, with a focus on medical tests used for screening, diagnosis and monitoring chronic disease. She is an NHMRC Fellow, and a member of the Medical Services Advisory Committee Evaluation Sub-Committee which critically assesses the evidence supporting applications for new listings on the Medical Benefits Scheme. The quality and impact of Professor Bell’s work has been recognised by awards including a Robinson Fellowship through the University of Sydney (2023) and an Australasian Epidemiological Association Mid-Career Researcher Professional Development Prize (2022).

Australian innovators create superior surgical screws for orthopaedic surgeries
Not all orthopaedic implants are created equal. Surgeons repair bone fractures using metal plates and screws but sometimes the screws loosen and the surgery needs to be repeated. Previous expandable screws increased screw fixation strength but were more difficult (or impossible) to remove and increased surgery time.

Research Excellence: Strengthening the evidence base for suicide prevention
Professor Jane Pirkis is the Director of the Centre for Mental Health and Community Wellbeing at the University of Melbourne. With a background in public health, Professor Pirkis has worked in the area of suicide prevention for over 25 years, contributing to knowledge about which interventions are effective in preventing suicide. Professor Pirkis’s work has also emphasised media-based interventions and interventions that involve restricting access to means of suicide. Professor Pirkis is the recipient of The University of Melbourne’s Marles Medal (2021) and is also the recipient of a Distinguished Alumni Award at the University of Tasmania (2017) and has received a Lifetime Research LIFE Award through Suicide Prevention Australia (2010).

Speaking of Science: Unlocking the power of Indigenous co-design and intervention: Transformative outcomes through authentic collaboration
National Reconciliation Week is a time for all Australians to learn about our shared histories, cultures, and achievements, and to explore how each of us can join the national efforts towards achieving national reconciliation.
In this Speaking of Science webinar held during National Reconciliation Week (27 May – 3 June 2024), we were joined by distinguished researcher and Indigenous leader, Professor Maree Toombs (Professor of Aboriginal and Torres Strait Islander Health in the University of New South Wales School of Population Health) who walked us through an incredibly moving presentation.

Research Excellence: A new paradigm for how APOE genotype affects brain lipid homeostasis and dementia risk
Professor Anthony Don is Professor of Medical Biochemistry in the School of Medical Sciences at the University of Sydney. His team develops and applies advanced mass spectrometry methods to investigate how alterations to brain lipid metabolism with ageing lead to dementia, develop neuroprotective therapeutics, and discover new biomarkers for demyelinating diseases. His research has uncovered deficits in lipid metabolism that destabilise myelin in the course of normal ageing and early in Alzheimer’s disease pathogenesis. He also developed and coordinates the popular masters-level unit of study, Advances in Disease Diagnosis and Treatment.

Redefining resilience research for Aboriginal and Torres Strait Islander adolescents
It is well known that Aboriginal and Torres Strait Islander peoples’ conceptions of health and wellbeing and life experiences differ vastly from mainstream populations.

Research Excellence: Novel interventions to treat and cure acute and chronic viral infections
Professor Sharon Lewin is the Director of the Peter Doherty Institute for Infection and Immunity at the University of Melbourne. Her research has focused on strategies to achieve an HIV cure, enhancing clinical outcomes for people living with HIV and hepatitis B and the identification of novel treatments for COVID-19. She is internationally known for her development of laboratory models to study HIV latency and for leading innovative early phase clinical trials aimed at reversing HIV latency. Professor Lewin has received Melburnian of the Year (2014), the Peter Wills Medal from Research Australia (2015), Officer of the Order of Australia (2019), and Medal for Outstanding Female Researcher by the Australian Academy of Health and Medical Sciences (2022).

Research Excellence: Pioneering Early Cancer Detection through Nanotechnology
Dr Jiayan Liao is a dedicated researcher specialising in the field of nanotechnology, nanomedicine, biomedical engineering, and their applications in medical diagnostics. Dr Liao’s research focuses on developing innovative diagnostic tools for early cancer detection, leveraging photonics, fluorescent nanoprobes, and artificial intelligence for precise detection of single-molecule biomarkers in diseases and cancers. Dr Liao is contributing to the advancement of diagnostic methodologies and technologies, aiming for non-invasive, early detection methods to improve patient outcomes.

Budget 2024–25
The Budget 2024–25, delivered on 14 May 2024, confirms the Australian Government’s ongoing commitment to supporting health and medical research and its translation into new health treatments and technologies to improve the health of the Australian community.

Research Excellence: Solving Australia's Hypertension Treatment Problem
Professor Alta Schutte, SHARP Professor and Principal Theme Lead of Cardiac, Vascular and Metabolic Medicine at the University of New South Wales and The George Institute for Global Health, focuses on implementing effective scalable interventions for global blood pressure control. Appointed Co-Chair of the National Hypertension Taskforce in 2022, she was recognised in 2023 as the Leading Researcher in Vascular Medicine by The Australian. Notably, she received the 2022 Harriet Dustan Award from the American Heart Association and the 2023 Peter Sleight Excellence award from the World Hypertension League. Her impactful work extends to improving cardiovascular health in Australia and beyond.

Over $77 million in funding to be shared in national clinical trials and cohort studies
High-quality national clinical trials and cohort studies aiming to improve the health and wellbeing of all Australians will receive over $77 million in funding under the National Health and Medical Research Council’s (NHMRC) Clinical Trials and Cohort Studies grant scheme.

Life-giving oils: low omega-3 fatty acid linked to early preterm birth and lower brain development
Preterm birth occurs in approximately 1 in 10 infants globally. It causes about three-quarters of near-birth deaths and more than half of newborn deaths.

A $411 million commitment for researchers to bring their discoveries to life
The National Health and Medical Research Council (NHMRC) continues to invest in our nation’s health and medical research sector, with over $411 million awarded to 229 outstanding researchers to investigate Australia’s greatest health challenges.

Uncovering the deep, dark secrets of pathogen genomes to save lives
Professor Ben Howden, from the University of Melbourne at the Doherty Institute, is a renowned clinician researcher whose dedicated focus on public health microbiology, genomics and antimicrobial resistance (AMR) has impacted thousands of lives.

Over $15 million for research collaborations to tackle healthcare policies and practice
With the announcement of 12 collaborative health and medical research projects today, Australian researchers are set to improve the translation and delivery of collaborative research outcomes into healthcare policy and practice.

A $5 million boost into furthering the quality and safety of telehealth
Six expert teams will share in over $5 million in funding to stimulate research into ensuring the quality and safety of telehealth, and its potential to achieve positive health outcomes under the National Health and Medical Research Council’s (NHMRC) Targeted Call for Research (TCR): Ensuring the quality and safety of telehealth 2023.

Speaking of Science: Towards a National Indigenous Genomics Agenda
Harnessing the power of research by combining genomics, precision medicine and public heath can help to address the long-term health and wellbeing of Aboriginal and Torres Strait Islander people.

Research Excellence: Designing adaptive strategies to drive tuberculosis towards elimination
Dr Romain Ragonnet is a Senior Research Fellow in the Epidemiological Modelling Unit at Monash University. Dr Ragonnet specialises in the mathematical modelling of tuberculosis (TB) and COVID-19, and his notable contributions include the first-ever quantification of TB mortality and self-recovery rates. Dr Ragonnet has advised various governments of lower-middle-income countries in the Asia-Pacific region to assist the local control of TB and COVID-19. He also initiated and led multiple cross-disciplinary collaborations, creating a strong network of world-leading experts that spans mathematics, medical ethics, biostatistics, economics, and clinical trials.

Getting adolescents active for health benefits
Less than 10% of adolescents globally, including in Australia, do enough physical activity to align with the amount required for young people to be healthy.

Research Excellence: Unlocking molecular vulnerabilities in childhood brain cancers
Dr Sean Humphrey leads the Functional Phosphoproteomics Laboratory at the Murdoch Children’s Research Institute. Dr Humphrey’s research uses cutting-edge mass spectrometers to create detailed molecular maps that capture how cells communicate and process information by regulating proteins. Dr Humphrey completed his PhD at the University of New South Wales before moving to Germany to undertake post-doctoral training at the Max Planck Institute of Biochemistry in Munich. Dr Humphrey’s research pinpoints key molecular signals that are dysregulated in human disease, uncovering a myriad of new targets for future therapies.

Addictive brain changes linked to obesity and simple supplement shows promise
When exposed to highly palatable (yummy) foods, some people overeat and have trouble regulating their intake long-term.

Research Excellence: Epidemiology and equity of kidney failure in Australasia
Dr Johanna Birrell is a general physician and advanced trainee in public health medicine. Dr Birrell has trained in both Australia and New Zealand and has a particular interest in rural health, Indigenous health, and health services research. Dr Birrell is completing her postdoctoral studies at the University of Sydney with concurrent clinical work. Her research explores geographic variation in kidney failure epidemiology and access to care across Australia and New Zealand. Dr Birrell has received awards including the Royal Australasian College of Physicians 2023 Aotearoa Trainee Research Award for Excellence in the Field of Adult Medicine and the Gerry Murphy Prize in 2022.

Honouring the achievements and dedication of Australian health and medical researchers
The National Health and Medical Research Council (NHMRC) has honoured the outstanding achievements with its annual Research Excellence Awards announced this evening in Canberra.

10 of the Best: Recognising Australia’s top researchers delivering extraordinary outcomes
The National Health and Medical Research Council (NHMRC) has released the 15th edition of its ‘10 of the Best’ publication, showcasing the calibre of our nation’s health and medical researchers working to prevent disease, improve detection and treatment methods, increase our understanding of common health conditions and deliver extraordinary outcomes.

$5 million towards Australian research to improve climate-related health outcomes
The National Health and Medical Research Council (NHMRC) has released Grant Opportunity Guidelines for a Targeted Call for Research (TCR) into 2024.

Speaking of Science: International Women’s Day 2024 - Inspire Inclusion
International Women’s Day represents a day of collective global activism and celebration that belongs to all of those committed to forging women’s equality.
In this Speaking of Science webinar held for International Women’s Day, we were joined by members of NHMRC’s Research Committee to discuss this year’s theme of ‘Inspire Inclusion’.

Speaking of Science: Ovarian Cancer Awareness Month- Early detection, risk prediction and improving prognosis
Around 1,786 new cases of ovarian cancer in Australia were estimated to have been diagnosed in 2023, which is the equivalent of a 1 in 87 lifetime risk.
In our first Speaking of Science webinar, held for Ovarian Cancer Awareness Month, we were joined by international expert in ovarian cancer research, Professor Susan Ramus (Professor of Molecular Oncology in the School of Clinical Medicine at the University of New South Wales).

NHMRC Update on the Australian Dietary Guidelines
The National Health and Medical Research Council (NHMRC) is currently undertaking a review of the Australian Dietary Guidelines. The updated guidelines are scheduled for delivery in 2026.

Growing up and getting stronger: improving the long-term health of premature babies
In the early 1970s, Professor Lex Doyle watched as ventilators were introduced in Australian hospitals to help premature babies breathe.

Accelerating change in driver safety screening
While many older Australians value the independence of driving and continue to do so safely throughout their lives, for others, the changes that occur with aging may take them off the road.

$2.8 million for global alliance for chronic diseases research
Research focused on non-communicable disease (NCD) prevention among vulnerable communities in Australia and Nepal will share in almost $2.8 million in grant funding through the National Health and Medical Research Council (NHMRC) Global Alliance for Chronic Diseases (GACD) scheme.

Harnessing the power of natural immunity to extend vaccine protection
Associate Professor Linda Wakim is focused on using our body’s own immune defence system to improve vaccines by providing longer lasting protection against viruses.

Community-designed and delivered suicide intervention
Warning: Some people may find parts of this content confronting. If this material raises any distress, contact Lifeline on 13 11 14, Call 13YARN or Kids Helpline on 1800 55 1800.
A self-described grassroots Aboriginal researcher, Professor Maree Toombs is responsible for developing the first Indigenous-led and designed suicide intervention training program in Australia, creating space for connection to traditional lands and culture as part of life-saving support.

Fighting biofilms with a Trojan Horse
Dr Nicky Thomas started his career as a pharmacist. During his PhD, he was investigating how encasing medicine in lipid droplets could improve its efficacy when he was asked: can this lipid technology be used to treat biofilms?