Centering Indigenous research excellence now and into the future
NHMRC is committed to improving the health of Aboriginal and Torres Strait Islander peoples through funding research of the highest quality, integrity and excellence. We also encourage applications across our grant funding program that address Aboriginal and Torres Strait Islander health.
Speaking of Science: Breast Cancer Awareness Month with Professor Belinda Parker
Did you know that breast cancer is the second most common cancer to cause death in women? In Australia, 1 in 7 women will be diagnosed with breast cancer in their lifetime.
At the intersection of science and art
There’s an area of health and medical research, where scientific discoveries are made and are accompanied by artistic imagery that holds both aesthetic power and major promise for further breakthroughs. This area lies at the intersection of science and art.
Speaking of Science: SOLVEing Coronary Heart Disease with Professor Julie Redfern
Cardiovascular disease is the world’s number one killer.
On a national scale, coronary heart disease is the leading single cause of disease burden in Australia and causes 11% of all deaths, sparking a real need to make transformative improvements in cardiovascular health management for all Australians.
Unified responses to youth substance use and mental disorders
Australia, like many other countries, is facing increasing rates of mental disorders and substance use. Globally, substance use, depression and anxiety disorders are among the leading causes of disease burden in young people. Yet they are treated in isolation, stalling discovery, prevention and treatment.
Upskilling gynaecology surgeons for better, less invasive surgical procedures and happier patients
Hysterectomy is the most common major gynaecological procedure Australian women will require in their lifetimes. Yet, up to 2 in 10 patients have developed severe complications following outdated open surgery.
$60 million in funding announced for new Centres of Research Excellence
An investment of $60 million will support researchers to pursue collaborative research that aims to improve health outcomes by translating health and medical research into policy and/or practice funded through the National Health and Medical Research Council’s (NHMRC) Centre of Research Excellence (CRE) scheme.
Speaking of Science: Synthetic Biology (designer cells and antibodies) with Professor Shalin Naik
National Science Week is an annual celebration that promotes and encourages interest in STEMM and acknowledges the contributions of Australian scientists to our ever-growing world of knowledge.
In this Speaking of Science webinar held during National Science Week (10 August – 18 August 2024), we were joined by the inspirational cell biologist and Laboratory Head at WEHI and the University of Melbourne, Professor Shalin Naik. Professor Naik is well versed in communicating complex science concepts across to the public in more simple ways where possible, and without belittling the important work that underlies it. In this webinar, he did just that!
Speaking of Science: International Research Translation Practice
Knowledge gained through research underpins improvements in Australia's health and medical services. This research can be fundamental or can be applied, directly addressing clinical problems, public policy, quality of life and environmental health issues or the provision of health services.
Research Excellence: Structure, function, and modulation of peptide hormone G protein-coupled receptors
Professor Patrick Sexton is the Professor of Pharmacology at the Monash Institute of Pharmaceutical Sciences and is the Director at the ARC Centre for Cryo-electron Microscopy of Membrane Proteins. Professor Sexton is a leader in progressing our understanding of G protein-coupled receptors (GPCRs), particularly allosteric modulation and biased agonism, and applying cryo-EM to study structure and dynamics of GPCRs. He is a Clarivate Analytics highly cited researcher and an elected Fellow of the British Pharmacological Society (BPS). Professor Sexton is also the co-founder of Septerna Inc and DACRA Tx and has been the recipient of many awards for his scientific contributions that have had major impacts on biological chemistry research.
Celebrating a 25-year legacy of Aboriginal and Torres Strait Islander health research with NHMRC
Professor Yvonne Cadet-James, the pioneering researcher, academic, mentor, registered nurse and midwife is celebrating a 25-year legacy of Aboriginal and Torres Strait Islander health research at the National Health and Medical Research Council (NHMRC).
Research Excellence: Advancing health equity of the Aboriginal and Torres Strait Islander population
Associate Professor Odette Pearson is of Eastern Yalanji and Torres Strait Islander descent and coleads the Aboriginal Health Equity Theme, South Australian Health and Medical Research Institute. Her research focus is improving chronic disease and ageing outcomes of Aboriginal and Torres Strait Islander peoples through policy and guideline development and implementing and evaluating real world health and social interventions. Aboriginal leadership, governance and community and cross sector partnerships are foundations of her research. A/Prof Pearson has received the Lowitja Institute Patricia Anderson Leader in Aboriginal Research (2023), UniSA Alumini Award for Research in Aboriginal Health (2022) and The Diane Ranck, SAHMRI award for Leadership in Research (2022).
Speaking of Science: International Men’s Health Week
For the 30th anniversary of International Men’s Health Week (10–16 June 2024), NHMRC shined an important light on key issues impacting the health and wellbeing of Australian men and boys, focusing on the 3 pillars of health: physical, mental and emotional.
Research Excellence: Developing novel gene expression control mechanisms for ALS gene therapies
Professor Roger Chung is the Professor of Neurobiology and Neurochemistry, and Deputy Dean (Research and Innovation) in the Faculty of Medicine, Health and Human Sciences at Macquarie University. Professor Chung’s research employs a multi-disciplinary approach to understanding the biochemical, molecular and cellular mechanisms that underpin how neurons respond to injury or neurodegenerative disease, and how non-neuronal cells (glia) are involved in modulating this process. Professor Chung is the co-founder and Chief Scientific Officer of CelosiaTX and also leads the Neurochemistry and Molecular Therapeutics Group within the Macquarie University Centre for Motor Neuron Disease Research.
Research Excellence: Driving the transition to high value testing to benefit the health of all
Professor Katy Bell is a clinical epidemiologist and health services researcher at the Sydney School of Public Health. Professor Bell’s research evaluates the clinical effectiveness of healthcare, with a focus on medical tests used for screening, diagnosis and monitoring chronic disease. She is an NHMRC Fellow, and a member of the Medical Services Advisory Committee Evaluation Sub-Committee which critically assesses the evidence supporting applications for new listings on the Medical Benefits Scheme. The quality and impact of Professor Bell’s work has been recognised by awards including a Robinson Fellowship through the University of Sydney (2023) and an Australasian Epidemiological Association Mid-Career Researcher Professional Development Prize (2022).
Australian innovators create superior surgical screws for orthopaedic surgeries
Not all orthopaedic implants are created equal. Surgeons repair bone fractures using metal plates and screws but sometimes the screws loosen and the surgery needs to be repeated. Previous expandable screws increased screw fixation strength but were more difficult (or impossible) to remove and increased surgery time.
Research Excellence: Strengthening the evidence base for suicide prevention
Professor Jane Pirkis is the Director of the Centre for Mental Health and Community Wellbeing at the University of Melbourne. With a background in public health, Professor Pirkis has worked in the area of suicide prevention for over 25 years, contributing to knowledge about which interventions are effective in preventing suicide. Professor Pirkis’s work has also emphasised media-based interventions and interventions that involve restricting access to means of suicide. Professor Pirkis is the recipient of The University of Melbourne’s Marles Medal (2021) and is also the recipient of a Distinguished Alumni Award at the University of Tasmania (2017) and has received a Lifetime Research LIFE Award through Suicide Prevention Australia (2010).
Speaking of Science: Unlocking the power of Indigenous co-design and intervention: Transformative outcomes through authentic collaboration
National Reconciliation Week is a time for all Australians to learn about our shared histories, cultures, and achievements, and to explore how each of us can join the national efforts towards achieving national reconciliation.
In this Speaking of Science webinar held during National Reconciliation Week (27 May – 3 June 2024), we were joined by distinguished researcher and Indigenous leader, Professor Maree Toombs (Professor of Aboriginal and Torres Strait Islander Health in the University of New South Wales School of Population Health) who walked us through an incredibly moving presentation.
Research Excellence: A new paradigm for how APOE genotype affects brain lipid homeostasis and dementia risk
Professor Anthony Don is Professor of Medical Biochemistry in the School of Medical Sciences at the University of Sydney. His team develops and applies advanced mass spectrometry methods to investigate how alterations to brain lipid metabolism with ageing lead to dementia, develop neuroprotective therapeutics, and discover new biomarkers for demyelinating diseases. His research has uncovered deficits in lipid metabolism that destabilise myelin in the course of normal ageing and early in Alzheimer’s disease pathogenesis. He also developed and coordinates the popular masters-level unit of study, Advances in Disease Diagnosis and Treatment.
Research Excellence: Novel interventions to treat and cure acute and chronic viral infections
Professor Sharon Lewin is the Director of the Peter Doherty Institute for Infection and Immunity at the University of Melbourne. Her research has focused on strategies to achieve an HIV cure, enhancing clinical outcomes for people living with HIV and hepatitis B and the identification of novel treatments for COVID-19. She is internationally known for her development of laboratory models to study HIV latency and for leading innovative early phase clinical trials aimed at reversing HIV latency. Professor Lewin has received Melburnian of the Year (2014), the Peter Wills Medal from Research Australia (2015), Officer of the Order of Australia (2019), and Medal for Outstanding Female Researcher by the Australian Academy of Health and Medical Sciences (2022).
Research Excellence: Pioneering Early Cancer Detection through Nanotechnology
Dr Jiayan Liao is a dedicated researcher specialising in the field of nanotechnology, nanomedicine, biomedical engineering, and their applications in medical diagnostics. Dr Liao’s research focuses on developing innovative diagnostic tools for early cancer detection, leveraging photonics, fluorescent nanoprobes, and artificial intelligence for precise detection of single-molecule biomarkers in diseases and cancers. Dr Liao is contributing to the advancement of diagnostic methodologies and technologies, aiming for non-invasive, early detection methods to improve patient outcomes.
Research Excellence: Solving Australia's Hypertension Treatment Problem
Professor Alta Schutte, SHARP Professor and Principal Theme Lead of Cardiac, Vascular and Metabolic Medicine at the University of New South Wales and The George Institute for Global Health, focuses on implementing effective scalable interventions for global blood pressure control. Appointed Co-Chair of the National Hypertension Taskforce in 2022, she was recognised in 2023 as the Leading Researcher in Vascular Medicine by The Australian. Notably, she received the 2022 Harriet Dustan Award from the American Heart Association and the 2023 Peter Sleight Excellence award from the World Hypertension League. Her impactful work extends to improving cardiovascular health in Australia and beyond.
Speaking of Science: Towards a National Indigenous Genomics Agenda
Harnessing the power of research by combining genomics, precision medicine and public heath can help to address the long-term health and wellbeing of Aboriginal and Torres Strait Islander people.
Research Excellence: Designing adaptive strategies to drive tuberculosis towards elimination
Dr Romain Ragonnet is a Senior Research Fellow in the Epidemiological Modelling Unit at Monash University. Dr Ragonnet specialises in the mathematical modelling of tuberculosis (TB) and COVID-19, and his notable contributions include the first-ever quantification of TB mortality and self-recovery rates. Dr Ragonnet has advised various governments of lower-middle-income countries in the Asia-Pacific region to assist the local control of TB and COVID-19. He also initiated and led multiple cross-disciplinary collaborations, creating a strong network of world-leading experts that spans mathematics, medical ethics, biostatistics, economics, and clinical trials.
Research Excellence: Unlocking molecular vulnerabilities in childhood brain cancers
Dr Sean Humphrey leads the Functional Phosphoproteomics Laboratory at the Murdoch Children’s Research Institute. Dr Humphrey’s research uses cutting-edge mass spectrometers to create detailed molecular maps that capture how cells communicate and process information by regulating proteins. Dr Humphrey completed his PhD at the University of New South Wales before moving to Germany to undertake post-doctoral training at the Max Planck Institute of Biochemistry in Munich. Dr Humphrey’s research pinpoints key molecular signals that are dysregulated in human disease, uncovering a myriad of new targets for future therapies.
Research Excellence: Epidemiology and equity of kidney failure in Australasia
Dr Johanna Birrell is a general physician and advanced trainee in public health medicine. Dr Birrell has trained in both Australia and New Zealand and has a particular interest in rural health, Indigenous health, and health services research. Dr Birrell is completing her postdoctoral studies at the University of Sydney with concurrent clinical work. Her research explores geographic variation in kidney failure epidemiology and access to care across Australia and New Zealand. Dr Birrell has received awards including the Royal Australasian College of Physicians 2023 Aotearoa Trainee Research Award for Excellence in the Field of Adult Medicine and the Gerry Murphy Prize in 2022.
Speaking of Science: International Women’s Day 2024 - Inspire Inclusion
International Women’s Day represents a day of collective global activism and celebration that belongs to all of those committed to forging women’s equality.
In this Speaking of Science webinar held for International Women’s Day, we were joined by members of NHMRC’s Research Committee to discuss this year’s theme of ‘Inspire Inclusion’.
Speaking of Science: Ovarian Cancer Awareness Month- Early detection, risk prediction and improving prognosis
Around 1,786 new cases of ovarian cancer in Australia were estimated to have been diagnosed in 2023, which is the equivalent of a 1 in 87 lifetime risk.
In our first Speaking of Science webinar, held for Ovarian Cancer Awareness Month, we were joined by international expert in ovarian cancer research, Professor Susan Ramus (Professor of Molecular Oncology in the School of Clinical Medicine at the University of New South Wales).
Growing up and getting stronger: improving the long-term health of premature babies
In the early 1970s, Professor Lex Doyle watched as ventilators were introduced in Australian hospitals to help premature babies breathe.
Accelerating change in driver safety screening
While many older Australians value the independence of driving and continue to do so safely throughout their lives, for others, the changes that occur with aging may take them off the road.
Harnessing the power of natural immunity to extend vaccine protection
Associate Professor Linda Wakim is focused on using our body’s own immune defence system to improve vaccines by providing longer lasting protection against viruses.
Community-designed and delivered suicide intervention
Warning: Some people may find parts of this content confronting. If this material raises any distress, contact Lifeline on 13 11 14, Call 13YARN or Kids Helpline on 1800 55 1800.
A self-described grassroots Aboriginal researcher, Professor Maree Toombs is responsible for developing the first Indigenous-led and designed suicide intervention training program in Australia, creating space for connection to traditional lands and culture as part of life-saving support.
Fighting biofilms with a Trojan Horse
Dr Nicky Thomas started his career as a pharmacist. During his PhD, he was investigating how encasing medicine in lipid droplets could improve its efficacy when he was asked: can this lipid technology be used to treat biofilms?
Improving fertility treatment through innovation
Professor Robert Gilchrist is a part of a bench-to-bedside research success story, innovating existing infertility treatments to offer a less invasive and cheaper alternative to in-vitro fertilisation (IVF).
Mentors inspire an Indigenous research career with impact
Professor Cath Chamberlain, a Palawa woman of the Trawlwoolway clan (Tasmania), received an NHMRC Early Career Fellowship in 2014 to find culturally safe ways to improve cardiometabolic health outcomes in Aboriginal and Torres Strait Islander mothers.
Driving change in aged care pharmacy practices through data
Having practised as a hospital pharmacist by day and a residential aged care pharmacist by night, Dr Lisa Pont naturally began to think about how pharmacists could work differently as part of her research.
Enhancing future pain treatments using venoms
Professor Richard Lewis and his team from the Institute of Molecular Bioscience at University of Queensland made a notable discovery early in their research after a lab assistant observed one could milk cone snails for venom much more quickly if you gave them 'a poke or two'.
Delivering a legacy of culturally safe maternity care
Professor Rhonda Marriott AM, a descendant of Nyikina people of the Kimberley, has devoted five decades to nursing and midwifery in clinical, academic and research roles.
Research Excellence: Supporting healing and recovery for Aboriginal and Torres Strait Islander survivors of childhood sexual abuse
Dr Graham Gee is an Aboriginal-Chinese man, also with Celtic heritage, originally from Darwin. His Aboriginal-Chinese grandfather was born near Belyuen on Larrakia Country. Dr Gee is a clinical psychologist and has worked at the Victorian Aboriginal Health Service for 11 years before taking up a research position at the Murdoch Children’s Research Institute. His early career research focused on Aboriginal and Torres Strait Islander mental health, social and emotional wellbeing, resilience and complex trauma. In 2022, Dr Gee commenced working in partnership with several Victorian Aboriginal services dedicated to healing child sexual abuse. Read more to find out more about Dr Gee’s research, in his own words.
Research Excellence: Microelectrode recordings from the vagus nerve in awake humans
Professor Vaughan Macefield is the Professor of Neuroscience in the Department of Neuroscience at Monash University. Professor Macefield specialises in recording from single nerve fibres via microelectrodes inserted into the peripheral nerves of awake human participants. He is best known for developing the methodology for recording the firing properties of single, type-identified, sympathetic neurones supplying muscle and skin, and for developing the methodology for recording muscle sympathetic nerve activity at the same time as performing functional magnetic resonance imaging of the brain. Read on to find out more about Professor Macefield's research, in his own words.
Tackling health challenges of the present and the future
As an infectious disease physician and researcher in HIV, vaccine development and the impact of the microbiome on human health, Professor Wesselingh brings a wealth of medical experience, clinical leadership as well as national and international success to this role.
Research Excellence: Understanding membrane protein structures
Dr Alastair Stewart, Head of the Institute’s Structural Biology Laboratory at the Victor Chang Cardiac Research Institute (VCCRI) focuses his research on understanding the mechanisms of how cells transport drug molecules using cyro-electron microscopy technology. Based within VCCRI’s Innovation Centre, Dr Stewart’s research involves generating detailed information on the function of membrane protein structures, providing a template to better understand drug interactions within the body. Read on to find out more about Dr Stewart’s research, in his own words.
Research Excellence: trialling women's testosterone therapy
Professor Susan Davis AO, Head of the Monash University Women’s Health Research Program, focuses her research on understanding the role of sex hormones, particularly testosterone, in women’s health. Her program of research involves a series of innovative, complementary clinical trials to determine if the hormone can serve as a new therapy to protect against leading causes of ill health in postmenopausal women. Read on to find out more about Professor Davis’s research, in her own words.
Research Excellence: predicting gastric cancer
Dr Doug Tjandra is an advanced trainee in gastroenterology at The Royal Melbourne Hospital with an interest in preventing gastrointestinal cancers and immunotherapy-related complications of the gastrointestinal tract and liver.
Research excellence: understanding the first few weeks of pregnancy
Professor Jose Polo’s work in epigenetics spans diverse fields, including cellular reprogramming, embryogenesis, neurobiology, immunology and cancer. His Synergy Grant brings together a multidisciplinary team who will combine the latest advances in models of early development, genetics and molecular biology to determine how the early placenta produced by the embryo burrows into the uterus and keeps developing during the entire pregnancy.
Research Excellence: rapidly detecting emerging viruses
It is challenging to contemplate, but the world can expect to experience pandemics like COVID-19, and perhaps even larger in scale, in the future. Professor Eddie Holmes is developing a pandemic radar to rapidly detect emerging viruses and determine which are most likely to have pandemic potential. His research focuses on understanding the fundamental mechanisms of virus ecology and evolution, as well as how viruses jump species boundaries to emerge and cause disease in new hosts.
Excellence in ethics and integrity
Reverend Kevin McGovern, recipient of the 2023 NHMRC Ethics and Integrity Award, is one of Australia’s leading ethicists, active in education, research and policy for over 25 years. Throughout his professional life as a parish priest, academic and community leader, Reverend McGovern has brought to innumerable discussions and debates the highest quality and intensity of consideration. His reputation for the courage of his convictions and his openness and respect for others with a diversity of views is unparalleled.
Excellence in consumer engagement: optimising the lives of people with aphasia
The Queensland Aphasia Research Centre (QARC) brings together people with aphasia, their families and friends, clinicians and researchers in the collaborative development of innovative and novel health interventions that transform lives. At NHMRC's Research Excellence Awards in March, QARC received the 2023 NHMRC Consumer Engagement Award, which recognises an individual, a group of individuals or an organisation that has made a long-term contribution to consumer and community involvement in health and medical research.
Research Excellence: A vision for the elimination of tuberculosis
Professor Greg Fox is a respiratory doctor and clinical trialist at the University of Sydney and Director of the Sydney Vietnam Institute who is contributing to the momentum towards tuberculosis (TB) elimination. Professor Fox received the 2021 NHMRC David Cooper Clinical Trials and Cohort Studies Award, recognising the highest ranked recipient in the Clinical Trials and Cohort Studies scheme.
Research excellence: Transforming midwifery in the Asia-Pacific region
Professor Caroline Homer AO is a midwife and maternal and newborn health researcher. Her research addresses maternal and newborn health issues, especially the role of midwives in improving outcomes in limited-resource settings, with a focus for more than 20 years on the Asia-Pacific region.