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Latest news and stories
Research Excellence: Unlocking molecular vulnerabilities in childhood brain cancers
Dr Sean Humphrey leads the Functional Phosphoproteomics Laboratory at the Murdoch Children’s Research Institute. Dr Humphrey’s research uses cutting-edge mass spectrometers to create detailed molecular maps that capture how cells communicate and process information by regulating proteins. Dr Humphrey completed his PhD at the University of New South Wales before moving to Germany to undertake post-doctoral training at the Max Planck Institute of Biochemistry in Munich. Dr Humphrey’s research pinpoints key molecular signals that are dysregulated in human disease, uncovering a myriad of new targets for future therapies.
Addictive brain changes linked to obesity and simple supplement shows promise
When exposed to highly palatable (yummy) foods, some people overeat and have trouble regulating their intake long-term.
Research Excellence: Epidemiology and equity of kidney failure in Australasia
Dr Johanna Birrell is a general physician and advanced trainee in public health medicine. Dr Birrell has trained in both Australia and New Zealand and has a particular interest in rural health, Indigenous health, and health services research. Dr Birrell is completing her postdoctoral studies at the University of Sydney with concurrent clinical work. Her research explores geographic variation in kidney failure epidemiology and access to care across Australia and New Zealand. Dr Birrell has received awards including the Royal Australasian College of Physicians 2023 Aotearoa Trainee Research Award for Excellence in the Field of Adult Medicine and the Gerry Murphy Prize in 2022.
Speaking of Science: International Women’s Day 2024 - Inspire Inclusion
International Women’s Day represents a day of collective global activism and celebration that belongs to all of those committed to forging women’s equality.
In this Speaking of Science webinar held for International Women’s Day, we were joined by members of NHMRC’s Research Committee to discuss this year’s theme of ‘Inspire Inclusion’.
Speaking of Science: Ovarian Cancer Awareness Month- Early detection, risk prediction and improving prognosis
Around 1,786 new cases of ovarian cancer in Australia were estimated to have been diagnosed in 2023, which is the equivalent of a 1 in 87 lifetime risk.
In our first Speaking of Science webinar, held for Ovarian Cancer Awareness Month, we were joined by international expert in ovarian cancer research, Professor Susan Ramus (Professor of Molecular Oncology in the School of Clinical Medicine at the University of New South Wales).
Growing up and getting stronger: improving the long-term health of premature babies
In the early 1970s, Professor Lex Doyle watched as ventilators were introduced in Australian hospitals to help premature babies breathe.
Accelerating change in driver safety screening
While many older Australians value the independence of driving and continue to do so safely throughout their lives, for others, the changes that occur with aging may take them off the road.
Harnessing the power of natural immunity to extend vaccine protection
Associate Professor Linda Wakim is focused on using our body’s own immune defence system to improve vaccines by providing longer lasting protection against viruses.
Community-designed and delivered suicide intervention
Warning: Some people may find parts of this content confronting. If this material raises any distress, contact Lifeline on 13 11 14, Call 13YARN or Kids Helpline on 1800 55 1800.
A self-described grassroots Aboriginal researcher, Professor Maree Toombs is responsible for developing the first Indigenous-led and designed suicide intervention training program in Australia, creating space for connection to traditional lands and culture as part of life-saving support.
Fighting biofilms with a Trojan Horse
Dr Nicky Thomas started his career as a pharmacist. During his PhD, he was investigating how encasing medicine in lipid droplets could improve its efficacy when he was asked: can this lipid technology be used to treat biofilms?
NHMRC Investigator Grants sets the standard for gender equity
It is an inspiring time for health and medical research in Australia as the National Health and Medical Research Council (NHMRC) sets the standard for achieving gender equity through its largest grant scheme, Investigator Grants.
Improving fertility treatment through innovation
Professor Robert Gilchrist is a part of a bench-to-bedside research success story, innovating existing infertility treatments to offer a less invasive and cheaper alternative to in-vitro fertilisation (IVF).
Mentors inspire an Indigenous research career with impact
Professor Cath Chamberlain, a Palawa woman of the Trawlwoolway clan (Tasmania), received an NHMRC Early Career Fellowship in 2014 to find culturally safe ways to improve cardiometabolic health outcomes in Aboriginal and Torres Strait Islander mothers.
Driving change in aged care pharmacy practices through data
Having practised as a hospital pharmacist by day and a residential aged care pharmacist by night, Dr Lisa Pont naturally began to think about how pharmacists could work differently as part of her research.
Enhancing future pain treatments using venoms
Professor Richard Lewis and his team from the Institute of Molecular Bioscience at University of Queensland made a notable discovery early in their research after a lab assistant observed one could milk cone snails for venom much more quickly if you gave them 'a poke or two'.
Delivering a legacy of culturally safe maternity care
Professor Rhonda Marriott AM, a descendant of Nyikina people of the Kimberley, has devoted five decades to nursing and midwifery in clinical, academic and research roles.
Research Excellence: Supporting healing and recovery for Aboriginal and Torres Strait Islander survivors of childhood sexual abuse
Dr Graham Gee is an Aboriginal-Chinese man, also with Celtic heritage, originally from Darwin. His Aboriginal-Chinese grandfather was born near Belyuen on Larrakia Country. Dr Gee is a clinical psychologist and has worked at the Victorian Aboriginal Health Service for 11 years before taking up a research position at the Murdoch Children’s Research Institute. His early career research focused on Aboriginal and Torres Strait Islander mental health, social and emotional wellbeing, resilience and complex trauma. In 2022, Dr Gee commenced working in partnership with several Victorian Aboriginal services dedicated to healing child sexual abuse. Read more to find out more about Dr Gee’s research, in his own words.
Research Excellence: Microelectrode recordings from the vagus nerve in awake humans
Professor Vaughan Macefield is the Professor of Neuroscience in the Department of Neuroscience at Monash University. Professor Macefield specialises in recording from single nerve fibres via microelectrodes inserted into the peripheral nerves of awake human participants. He is best known for developing the methodology for recording the firing properties of single, type-identified, sympathetic neurones supplying muscle and skin, and for developing the methodology for recording muscle sympathetic nerve activity at the same time as performing functional magnetic resonance imaging of the brain. Read on to find out more about Professor Macefield's research, in his own words.
Research Excellence: Understanding membrane protein structures
Dr Alastair Stewart, Head of the Institute’s Structural Biology Laboratory at the Victor Chang Cardiac Research Institute (VCCRI) focuses his research on understanding the mechanisms of how cells transport drug molecules using cyro-electron microscopy technology. Based within VCCRI’s Innovation Centre, Dr Stewart’s research involves generating detailed information on the function of membrane protein structures, providing a template to better understand drug interactions within the body. Read on to find out more about Dr Stewart’s research, in his own words.
Research Excellence: trialling women's testosterone therapy
Professor Susan Davis AO, Head of the Monash University Women’s Health Research Program, focuses her research on understanding the role of sex hormones, particularly testosterone, in women’s health. Her program of research involves a series of innovative, complementary clinical trials to determine if the hormone can serve as a new therapy to protect against leading causes of ill health in postmenopausal women. Read on to find out more about Professor Davis’s research, in her own words.
Research Excellence: predicting gastric cancer
Dr Doug Tjandra is an advanced trainee in gastroenterology at The Royal Melbourne Hospital with an interest in preventing gastrointestinal cancers and immunotherapy-related complications of the gastrointestinal tract and liver.
Research excellence: understanding the first few weeks of pregnancy
Professor Jose Polo’s work in epigenetics spans diverse fields, including cellular reprogramming, embryogenesis, neurobiology, immunology and cancer. His Synergy Grant brings together a multidisciplinary team who will combine the latest advances in models of early development, genetics and molecular biology to determine how the early placenta produced by the embryo burrows into the uterus and keeps developing during the entire pregnancy.
Research Excellence: rapidly detecting emerging viruses
It is challenging to contemplate, but the world can expect to experience pandemics like COVID-19, and perhaps even larger in scale, in the future. Professor Eddie Holmes is developing a pandemic radar to rapidly detect emerging viruses and determine which are most likely to have pandemic potential. His research focuses on understanding the fundamental mechanisms of virus ecology and evolution, as well as how viruses jump species boundaries to emerge and cause disease in new hosts.
Excellence in ethics and integrity
Reverend Kevin McGovern, recipient of the 2023 NHMRC Ethics and Integrity Award, is one of Australia’s leading ethicists, active in education, research and policy for over 25 years. Throughout his professional life as a parish priest, academic and community leader, Reverend McGovern has brought to innumerable discussions and debates the highest quality and intensity of consideration. His reputation for the courage of his convictions and his openness and respect for others with a diversity of views is unparalleled.
Excellence in consumer engagement: optimising the lives of people with aphasia
The Queensland Aphasia Research Centre (QARC) brings together people with aphasia, their families and friends, clinicians and researchers in the collaborative development of innovative and novel health interventions that transform lives. At NHMRC's Research Excellence Awards in March, QARC received the 2023 NHMRC Consumer Engagement Award, which recognises an individual, a group of individuals or an organisation that has made a long-term contribution to consumer and community involvement in health and medical research.
Research Excellence: A vision for the elimination of tuberculosis
Professor Greg Fox is a respiratory doctor and clinical trialist at the University of Sydney and Director of the Sydney Vietnam Institute who is contributing to the momentum towards tuberculosis (TB) elimination. Professor Fox received the 2021 NHMRC David Cooper Clinical Trials and Cohort Studies Award, recognising the highest ranked recipient in the Clinical Trials and Cohort Studies scheme.
Research excellence: Transforming midwifery in the Asia-Pacific region
Professor Caroline Homer AO is a midwife and maternal and newborn health researcher. Her research addresses maternal and newborn health issues, especially the role of midwives in improving outcomes in limited-resource settings, with a focus for more than 20 years on the Asia-Pacific region.
Research Excellence: New antibody therapies against malaria and COVID-19
Professor Wai-Hong Tham was one of four distinguished female researchers to receive 2022 NHMRC Elizabeth Blackburn Investigator Grant Awards. Her award was for the highest ranked female recipient (Leadership category) in the Basic Science research area of the Investigator Grants scheme. Professor Tham is Head of the division of Infectious Diseases and Immune Defence at WEHI and co-Chair of the WEHI Biologics Initiative.
Research Excellence: Identifying gaps and solutions needed for HIV elimination
Dr Tafi Marukutira is a medical doctor and public health researcher, specialising in infectious diseases epidemiology. Dr Marukutira received the 2022 NHMRC Frank Fenner Investigator Grant Award (Emerging Leadership), which recognises the highest ranked recipient in the Emerging Leadership Level 1 Investigator Grant category within the Basic Science or Public Health research areas, for his work on equitable access to HIV care and treatment.
Communities driving health care research
'It’s about coming with an open mind and heart, and willingness to deeply listen to community… to have any preconceptions challenged and re-learn ways of doing research' - Dr Veronica Matthews , co-lead investigator, STRengthening systems for InDigenous healthcare Equity (STRIDE)
Improving carer wellbeing and empowering Indigenous communities
Associate Professor Dina LoGiudice is a geriatrician and clinical researcher with a special interest in dementia and ageing well. For close to two decades, she has been studying the impacts of ageing and dementia in Aboriginal and Torres Strait Islander communities.
Smiles saved with a major improvement in dental health of young Aboriginal children
For much of his professional life in the United Kingdom, Professor Anthony Blinkhorn has focussed on improving the oral health of children in poorer communities through collaborative approaches with government agencies. This work saw him appointed as Chair of Population Oral Health at the University of Sydney in 2007, funded by the NSW Health Centre for Oral Health Strategy.
Mind the gap – Filling in the missing evidence for massive blood transfusion policy
Professor Jamie Cooper AO is Sir John Monash Distinguished Professor in the School of Public Health and Preventive Medicine at Monash University, and Senior Specialist in Intensive Care at The Alfred Hospital in Melbourne.
Healthier hearts in the tropical north
Professor Anna Ralph is a practicing medical specialist and leads the Global and Tropical Health division at Menzies School of Health Research in Darwin.
Unravelling genomes to find an answer
Autoimmune diseases account for one of the largest burdens of chronic disease on our health system. According to Professor Chris Goodnow FAA FRS, there are more than 100 autoimmune diseases that collectively affect 10% of people.
Lessons from the best to improve Indigenous health services: a collaborative learning approach
Professor Sarah Larkins has focused on improving equity in health care services in rural, remote and Indigenous populations since a medical education placement in the Northern Territory highlighted the tremendous inequities in health care access in the region.
Metal complexes for the treatment of age-related diseases of the brain
Dr Jeffrey Liddell from the University of Melbourne is a mid-career neurobiologist, with an interest in neurodegenerative diseases and understanding their underlying causes.
Born too soon – A better life for preterm babies
A major achievement for Associate Professor Shannon Simpson was the recent establishment of PELICAN (Prematurity’s Effects on the Lungs In Children and Adults Network), which she co-chairs with Dr Jenny Hallberg from the Karolinska Institute in Sweden.
Helping children get the best start to life
Professor Harriet Hiscock is a paediatrician researcher at the Murdoch Children's Research Institute. Her work focuses on keeping children out of hospital, reducing low value care, and improving access to and quality of care – especially mental health care.
Working towards gender equity in Investigator Grants
NHMRC has introduced new special measures under the Sex Discrimination Act 1984 to address systemic disadvantage faced by female and non-binary applicants to its Investigator Grant scheme.
Forging a farsighted agenda with a novel global way of thinking about science
The Human Frontier Science Program (HFSP) was established in 1990 to promote international collaboration in basic research focused on the elucidation of the sophisticated and complex mechanisms of living organisms. Since then, 1180 research grants have been awarded to more than 7500 researchers representing 71 nationalities, including Australia.
HFSP Secretary-General Professor Pavel Kabat introduces the program and three prominent researchers tell us how their HFSP grants advanced their research.
Making a decision to do the hard research, that’s what discovery is about
Deciding to commit to a research life is brave – so is committing to do the hard research. Professor Cath Chamberlain says with Aboriginal and Torres Strait Islander health, in particular, 'we are going to need to take some more risks to do things differently'.
Working beyond our own borders for a better world
Associate Professor Joshua Vogel is a Principal Research Fellow at the Burnet Institute in Melbourne, where he co-heads the Global Women’s and Newborn’s Health Group. His research focuses on addressing maternal and perinatal health issues affecting women and families in limited-resource settings. Associate Professor Vogel was the winner of the 2020 Peter Doherty Investigator Grant Award, and the Commonwealth Health Minister’s Award for Excellence in Health and Medical Research.
Getting to the cause of type 2 diabetes
The daily burden of living with diabetes can be significant. It’s estimated that people with diabetes face up to 180 diabetes-related decisions every day. That’s more than 65,000 extra decisions a year. These decisions can range from managing daily blood sugar levels, food intake and exercise to the management of serious diabetes complications.
Addressing Australia’s national transfusion research priorities
Professor Erica Wood is head of the Transfusion Unit at Monash University. Her research describes how blood is used in Australia, and how its use can be improved and made safer and more cost-effective. Through registry data and clinical trials, and studies of novel blood products, Professor Wood and her team aim to improve access and transfusion outcomes for patients.
Unlocking the secrets of the brain
Professor John Bekkers from the John Curtin School of Medical Research and his team are currently working on the neurons and circuits in the brain that underlie the sense of smell. His team focus on the olfactory cortex, a brain region that is responsible for our ability to recognise and remember odours.
Partnership with Aboriginal communities for a meaningful contribution
Professor Kate Conigrave from The University of Sydney is an Addiction Medicine Specialist and Public Health Physician based at Royal Prince Alfred Hospital. Her work combines treating individuals with alcohol, drug and tobacco problems, promoting the health of communities and research and teaching. She is currently the chair of the National Health and Medical Research Council's (NHMRC) Alcohol Working Group, which is charged with reviewing the guidelines to reduce the health risks from drinking alcohol.
Breathing easy – Improving access to respiratory disease rehabilitation
The average adult takes up to 20 breaths every minute, something most people give little thought. However, breathing can be a daily struggle for people with Chronic Obstructive Pulmonary Disease (COPD),an umbrella term for a group of lung conditions that includes emphysema, chronic bronchitis and chronic asthma.
Ensuring evidence is translated into practice
Professor Rachelle Buchbinder is a National Health and Medical Research Council (NHMRC) Senior Principal Research Fellow. She is the Director and Professor in the Monash University Department of Epidemiology & Preventive Medicine since 2007. Professor Rachelle Buchbinder's clinical practice is in conjunction with research involving multidisciplinary projects relating to arthritis and musculoskeletal condition.
Working to stop Parkinson's disease
Associate Professor Antony Cooper from the Garvan Institute of Medical Research is a cell and molecular biologist / geneticist with strong interests in elucidating how cellular dysfunction results in human diseases, with a specific interest in neurodegenerative disease such as Parkinson’s Disease. His research on neurodegenerative diseases focuses on understanding the basis of Parkinson’s Disease. Watch his story in the video below.