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In Australia, approximately 1.2 million people are affected by an immune-system disease. For a majority of these diseases, women are three times more likely to be afflicted than are men. As a group, immune-system diseases are the third leading cause of morbidity and mortality in the industrialised world, surpassed only by cancer and heart diseases.

The Australian Government has commissioned a review of the clinical effectiveness of 16 natural therapies excluded from private health insurance rebates. The Department of Health has engaged National Health and Medical Research Council (NHMRC) to assist in its review by commissioning evidence evaluations that will assess published scientific research on the excluded therapies.