Professor Benjamin Kile has turned his attention to looking at the link between dying cells, the inflammatory response and autoimmunity.
Understanding how blood cells die, which occurs naturally all the time, and what happens when these cells aren’t properly disposed of by the body, could be an important key in identifying causes of autoimmunity.
Professor Kile was previously highlighted in NHMRC’s Ten of the Best 2011 for his research into blood platelet survival. This work has informed the development of a cancer therapy that initially stalled due to proteins required for platelet cell survival being inadvertently targeted. The new cancer drug essentially tricks tumour cells into committing suicide by inhibiting another related protein, thereby ensuring the platelets survive.